
Active Pharmaceutical Ingredient and Intermediate Synthesis
Active pharmaceutical ingredient and intermediate synthesis
Using pharmaceutical manufacturing technology that we’ve developed since our founding in 1917 and an exceptional quality control system, we manufacture high-quality pharmaceuticals that provide customers peace of mind. We meet a diverse range of active pharmaceutical ingredient manufacturing needs on the part of pharmaceutical companies with technological capability and expertise from more than 40 years of experience synthesizing active pharmaceutical ingredients.
We operate a Pharmaceutical GMP-compliant plant in Omuta, Fukuoka. Our integrated approach to manufacturing the active pharmaceutical ingredients and intermediates our customers need extends from raw material acceptance to shipping of the final product. We've also put in place joint development structures that allow us to accommodate special requests from customers, for example to study synthesis routes. As a result, we're able to offer services that go beyond the domestic market, including export of active pharmaceutical ingredient to overseas pharmaceutical manufacturers and joint development of intermediates and active pharmaceutical ingredients at the request of overseas manufacturers.
Pharmaceutical synthesis

Principal reactions with which we have experience
- Esterification reactions
- Decarboxylation reactions
- Imino reactions
- Nitrate esterification reactions
- Bromination reactions
- Amidation reactions
- Amination reactions
- Alkylation reactions
- Hydrogenation reactions
- Grignard reactions
- Triazole addition reactions
- Alcohol reduction reactions
Equipment
We enforce thorough hygiene management at our production plants to maintain a high level of cleanliness at production facilities.
We create high quality products with our full line of equipment, including reaction units, dryers, mills, classifiers, and package fillers.
Synthesis reactors

Small synthesis reactors

Filtration equipment

Centrifugal separators

Filling and packaging equipment
